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Mutagenesis No formal experiments to assess the mutagenic prospective of morphine happen to be carried out. While in the released literature, morphine was identified for being mutagenic in vitro increasing DNA fragmentation in human T-cells. Morphine was noted to be mutagenic inside the in vivo mouse micronucleus assay and positive with the induction of chromosomal aberrations in mouse spermatids and murine lymphocytes.
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When taking morphine sulfate tablets: Do not change your dose. Get morphine sulfate tablets just as prescribed by your healthcare provider. Use the bottom dose probable for the shortest time desired.
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INDICATIONS AND Utilization Morphine sulfate tablets are opioid agonists indicated with the management of: Grown ups and pediatric patients weighing 50 kg and previously mentioned with acute pain significant adequate to involve an opioid analgesic and for which substitute treatment plans are insufficient.